Description

2-Chloro-4-(4-Trifluoromethyl-Phenyl)-Pyrimidine is a high-value halogenated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a chloro and a trifluoromethylphenyl group, makes it an essential intermediate for creating compounds with tailored electronic and steric properties. This product is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides where the pyrimidine core is a common bioactive motif.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: Versatile building block for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Ligand & Catalyst Development: Utilized in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Chloro-4-(4-Trifluoromethyl-Phenyl)-Pyrimidine
CAS No.	659729-15-4
Molecular Formula	C11H6ClF3N2
Molecular Weight	258.63 g/mol
Synonyms	2-Chloro-4-[4-(trifluoromethyl)phenyl]pyrimidine; 4-(4-Trifluoromethylphenyl)-2-chloropyrimidine; 2-Chloro-4-(α,α,α-trifluoro-p-tolyl)pyrimidine; Pyrimidine, 2-chloro-4-[4-(trifluoromethyl)phenyl]-; 659729-15-4
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development use. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to verify identity and purity. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all relevant specifications. We adhere to a strict quality management system to guarantee batch-to-batch consistency and supply reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.