Description

4-(4-tert-Butyl-Phenyl)-6-Chloro-Pyrimidine is a high-purity, halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals, where its specific substitution pattern enables precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or functional unit in the creation of organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create complex ligands for catalytic systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and scaled-up processes.
• Academic and R&D Laboratories: Utilized in fundamental chemical research for exploring new reaction pathways and heterocyclic chemistry.

Basic Information

Product Name	4-(4-tert-Butyl-Phenyl)-6-Chloro-Pyrimidine
CAS No.	659729-07-4
Molecular Formula	C14H15ClN2
Molecular Weight	246.74 g/mol
Synonyms	6-Chloro-4-(4-tert-butylphenyl)pyrimidine; 4-(4-tert-Butylphenyl)-6-chloropyrimidine; 4-(4-(tert-Butyl)phenyl)-6-chloropyrimidine; 6-Chloro-4-[4-(1,1-dimethylethyl)phenyl]pyrimidine; 4-(p-tert-Butylphenyl)-6-chloropyrimidine; 659729-07-4; tert-Butylphenyl chloropyrimidine
EINECS	Contact for details

Quality Control

Every batch of 4-(4-tert-Butyl-Phenyl)-6-Chloro-Pyrimidine is produced under strict quality management protocols. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure high purity and consistency that meets the stringent requirements of pharmaceutical and agrochemical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.