Description

Ethyl 4-Chloro-5-Isopropylpyrrolo[2,1-F][1,2,4]Triazine-6-Carboxylate is a high-value, heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it provides a versatile and functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly those targeting kinase inhibition or other biological pathways where the pyrrolotriazine core is active.
• Agrochemical Research: Serves as a building block for synthesizing new herbicides, fungicides, or insecticides with potentially improved efficacy and selectivity.
• Chemical Biology Probe Development: Used to create tool compounds for studying enzyme function and cellular signaling pathways in academic and industrial research settings.
• Material Science Precursor: Can be utilized in the synthesis of organic electronic materials or advanced polymers requiring specific heterocyclic architectures.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Library Synthesis for High-Throughput Screening: Employed in the parallel and combinatorial synthesis of diverse compound libraries to identify new lead structures in drug discovery.

Basic Information

Product Name	Ethyl 4-Chloro-5-Isopropylpyrrolo[2,1-F][1,2,4]Triazine-6-Carboxylate
CAS No.	658084-80-1
Molecular Formula	C₁₂H₁₄ClN₃O₂
Molecular Weight	267.71 g/mol
Synonyms	4-Chloro-5-(propan-2-yl)-6-(ethoxycarbonyl)pyrrolo[2,1-f][1,2,4]triazine; Ethyl 4-chloro-5-(1-methylethyl)pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate; 6-Carbethoxy-4-chloro-5-isopropylpyrrolo[2,1-f][1,2,4]triazine; Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid, 4-chloro-5-(1-methylethyl)-, ethyl ester; 658084-80-1; 4-Chloro-5-isopropyl-pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-5-Isopropylpyrrolo[2,1-F][1,2,4]Triazine-6-Carboxylate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled and stored accordingly. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.