Description

6-(2-Fluorobenzyl)-5,7-Dimethylpyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound is a critical building block for medicinal chemistry research and development, offering a versatile scaffold for creating novel therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Kinase Inhibitor Development: The pyrazolopyrimidine core is a privileged structure in the design of potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of tool compounds for studying enzyme function and cellular signaling pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	6-(2-Fluorobenzyl)-5,7-Dimethylpyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid
CAS No.	656818-36-9
Molecular Formula	C₁₇H₁₅FN₄O₂
Molecular Weight	326.33 g/mol
Synonyms	6-[(2-Fluorophenyl)methyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid; 6-(2-Fluorobenzyl)-5,7-dimethyl-1H-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid; 5,7-Dimethyl-6-(2-fluorobenzyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid; 656818-36-9; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 6-[(2-fluorophenyl)methyl]-5,7-dimethyl-; 6-(2-Fluorobenzyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 6-(2-Fluorobenzyl)-5,7-Dimethylpyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up work. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.