Description

4-(3,5-Difluorophenyl)Phenol is a high-purity fluorinated phenolic compound, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the unique reactivity imparted by the difluorophenyl and phenolic functional groups, enabling precise molecular construction. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing complex drug candidates, especially in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens in high-performance electronic displays.
• Polymer Chemistry: Acts as a monomer or chain modifier for engineering plastics and specialty polymers requiring thermal and chemical resistance.
• Organic Electronics: Employed in the synthesis of charge-transport materials and emissive layers for OLED devices.
• Cross-Coupling Reactions: A versatile substrate for Suzuki, Heck, and other palladium-catalyzed coupling reactions to create biaryl structures.

Basic Information

Product Name	4-(3,5-Difluorophenyl)Phenol
CAS No.	656304-67-5
Molecular Formula	C12H8F2O
Molecular Weight	206.19 g/mol
Synonyms	4-(3,5-Difluorophenyl)phenol; [1,1'-Biphenyl]-4-ol, 3',5'-difluoro-; 3',5'-Difluoro[1,1'-biphenyl]-4-ol; 4-Hydroxy-3',5'-difluorobiphenyl; (3,5-Difluorophenyl)phenol; Phenol, 4-(3,5-difluorophenyl)-; BRN 9079156
EINECS	Contact for details

Quality Control

Every batch of 4-(3,5-Difluorophenyl)Phenol is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality protocols are designed to meet the stringent standards of cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, the container should be purged with inert gas after each opening to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.