Description

2-(tert-Butyl)-7-Chloro-3-Iodo-5-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine is a high-value, multi-functional heterocyclic building block characterized by its unique halogenated and trifluoromethylated structure. This compound is engineered to serve as a critical intermediate in advanced synthetic chemistry, enabling the development of novel molecules with enhanced properties. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazolo[1,5-a]pyrimidine core.
• Material Science Research: Serves as a precursor for developing specialty chemicals, dyes, and functional materials due to its halogen and fluorine substituents.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Details
Product Name	2-(tert-Butyl)-7-Chloro-3-Iodo-5-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine
CAS No.	655235-52-2
Molecular Formula	C11H9ClF3IN3
Molecular Weight	429.56 g/mol
Synonyms	7-Chloro-3-iodo-5-(trifluoromethyl)-2-(tert-butyl)pyrazolo[1,5-a]pyrimidine; 2-tert-Butyl-7-chloro-3-iodo-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine; 655235-52-2; Pyrazolo[1,5-a]pyrimidine, 7-chloro-3-iodo-5-(trifluoromethyl)-2-(1,1-dimethylethyl)-; tert-Butyl Chloro Iodo Trifluoromethyl Pyrazolopyrimidine
EINECS	Contact for details

Quality Control

Every batch of 2-(tert-Butyl)-7-Chloro-3-Iodo-5-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.