Description

3-Bromo-2-(tert-Butyl)-7-Chloro-5-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its complex molecular architecture, featuring bromo, chloro, and trifluoromethyl substituents on a pyrazolopyrimidine core, makes it a versatile intermediate for constructing novel chemical entities. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor research and the development of small molecule therapeutics.
• Agrochemical Research: Used in the discovery and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure.
• Material Science: Serves as a precursor for creating specialty polymers, liquid crystals, or organic electronic materials due to its rigid, multi-substituted heterocyclic framework.
• Chemical Biology: Employed as a molecular probe or a tag in medicinal chemistry for structure-activity relationship (SAR) studies and target identification.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.

Basic Information

Product Name	3-Bromo-2-(tert-Butyl)-7-Chloro-5-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine
CAS No.	655235-50-0
Molecular Formula	C11H9BrClF3N3
Molecular Weight	368.56 g/mol
Synonyms	3-Bromo-2-tert-butyl-7-chloro-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine; 7-Chloro-3-bromo-2-(tert-butyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine; 2-(tert-Butyl)-3-bromo-7-chloro-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidine, 3-bromo-2-(1,1-dimethylethyl)-7-chloro-5-(trifluoromethyl)-; 655235-50-0
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-(tert-Butyl)-7-Chloro-5-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.