Description

5-(4-Chlorophenyl)-2-Phenyl-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine CAS NO 654053-57-3 is a high-value, heterocyclic organic compound featuring a pyrazolopyrimidine core substituted with chlorophenyl, phenyl, and trifluoromethyl groups. This specific molecular architecture makes it a critical advanced intermediate for research and development in modern pharmaceutical chemistry. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the research and synthesis of potential drug candidates, particularly in kinase inhibitor and anti-cancer therapeutic programs.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology Probe: Serves as a core scaffold for creating molecular probes to study biological pathways and enzyme functions in academic and industrial research.
• Material Science Research: Investigated as a precursor for organic electronic materials due to the presence of electron-withdrawing and donating groups on its fused ring system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects requiring this precise molecular entity.

Basic Information

Item	Details
Product Name	5-(4-Chlorophenyl)-2-Phenyl-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine
CAS No.	654053-57-3
Molecular Formula	C19H11ClF3N3
Molecular Weight	373.76 g/mol
Synonyms	5-(4-Chlorophenyl)-2-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine; 7-(Trifluoromethyl)-5-(4-chlorophenyl)-2-phenylpyrazolo[1,5-a]pyrimidine; 654053-57-3; Pyrazolo[1,5-a]pyrimidine, 5-(4-chlorophenyl)-2-phenyl-7-(trifluoromethyl)-; 5-(p-Chlorophenyl)-2-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 5-(4-Chlorophenyl)-2-Phenyl-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.