Description

Quinazoline, 8-Amino-3,4-Dihydro- (5Ci) is a high-purity, specialized heterocyclic organic compound serving as a critical building block in advanced chemical synthesis. Its value lies in its functionalized quinazoline core, which is essential for constructing complex molecular architectures with targeted biological or material properties. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinazoline-based drug candidates, particularly for oncology and central nervous system (CNS) targets.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and plant growth regulators that leverage the quinazoline scaffold.
• Material Science: Building block for creating organic semiconductors, liquid crystals, and advanced polymers with specific electronic or optical properties.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing chemical probes, enzyme inhibitors, and tool compounds for biological pathway analysis.
• Academic & Contract Research: Essential raw material for synthetic organic chemistry research, method development, and discovery chemistry in academic and CRO settings.
• Dye & Pigment Intermediate: Potential starting material for synthesizing specialized heterocyclic dyes and colorants.

Basic Information

Product Name	Quinazoline, 8-Amino-3,4-Dihydro- (5Ci)
CAS No.	653577-49-2
Molecular Formula	C9H9N3
Molecular Weight	159.19 g/mol
Synonyms	8-Amino-3,4-dihydroquinazoline; 3,4-Dihydro-8-aminoquinazoline; 8-Aminodihydroquinazoline; 8-Amino-1,2,3,4-tetrahydroquinazoline; 8-Aminoquinazoline, 3,4-dihydro-; Quinazoline, 8-amino-1,2,3,4-tetrahydro-; 5Ci-8-Aminodihydroquinazoline; 8-Amino-1,2,3,4-tetrahydro-quinazoline
EINECS	Contact for details

Quality Control

Our Quinazoline, 8-Amino-3,4-Dihydro- (5Ci) is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture and contamination. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.