Description

1-Cyclopentyl-3-(2,6-Difluoro-3,5-Dimethoxyphenyl)-7-(Methylsulfinyl)-3,4-Dihydropyrimido[4,5-D]Pyrimidin-2(1H)-One (Wxc02515) is a high-purity, advanced pharmaceutical intermediate belonging to the dihydropyrimidopyrimidinone class of heterocyclic compounds. This compound matters for its critical role as a key building block in the synthesis of sophisticated small-molecule therapeutics, particularly kinase inhibitors. Pharmaceutical R&D and process chemistry teams need this material for developing targeted drug candidates in oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold in the research and development of novel kinase inhibitor drugs.
• Oncology Drug Discovery: Used as a precursor in the synthesis of targeted cancer therapies due to its specific molecular architecture.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and cGMP manufacturing for Active Pharmaceutical Ingredient (API) production.
• Biochemical Research: Acts as a reference standard or a tool compound in enzymatic assays and structure-activity relationship (SAR) studies.
• Custom Synthesis: Provides a versatile starting point for medicinal chemists to create derivative libraries for high-throughput screening.

Basic Information

Product Name	1-Cyclopentyl-3-(2,6-Difluoro-3,5-Dimethoxyphenyl)-7-(Methylsulfinyl)-3,4-Dihydropyrimido[4,5-D]Pyrimidin-2(1H)-One (Wxc02515)
CAS No.	651734-99-5
Molecular Formula	C₂₀H₂₂F₂N₄O₄S
Molecular Weight	452.48 g/mol
Synonyms	WXC-02515; WXC02515; 1-Cyclopentyl-3-(2,6-difluoro-3,5-dimethoxyphenyl)-7-(methylsulfinyl)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one; 7-(Methylsulfinyl)-1-cyclopentyl-3-(2,6-difluoro-3,5-dimethoxyphenyl)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one; Dihydropyrimido[4,5-d]pyrimidinone derivative; CAS 651734-99-5
EINECS	Contact for details

Quality Control

Our 1-Cyclopentyl-3-(2,6-Difluoro-3,5-Dimethoxyphenyl)-7-(Methylsulfinyl)-3,4-Dihydropyrimido[4,5-D]Pyrimidin-2(1H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.