Description

Ethyl 4-(Cyclopropylamino)-2-(Methylthio)-Pyrimidine-5-Carboxylate is a high-purity, functionalized pyrimidine derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce cyclopropylamino and methylthio functionalities into target structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific pyrimidine cores.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialty chemicals.
• Research & Development: Serves as a versatile substrate in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	Ethyl 4-(Cyclopropylamino)-2-(Methylthio)-Pyrimidine-5-Carboxylate
CAS No.	651734-65-5
Molecular Formula	C11H15N3O2S
Molecular Weight	253.32 g/mol
Synonyms	Ethyl 4-(cyclopropylamino)-2-(methylthio)-5-pyrimidinecarboxylate; 4-(Cyclopropylamino)-2-(methylthio)pyrimidine-5-carboxylic Acid Ethyl Ester; 2-(Methylthio)-4-(cyclopropylamino)pyrimidine-5-carboxylic Acid Ethyl Ester; 5-Pyrimidinecarboxylic acid, 4-(cyclopropylamino)-2-(methylthio)-, ethyl ester; Ethyl 4-Cyclopropylamino-2-methylthiopyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our production of Ethyl 4-(Cyclopropylamino)-2-(Methylthio)-Pyrimidine-5-Carboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single impurity	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.