Description

n-Benzyl-2,6-Difluoro-3,5-Dimethoxyaniline is a high-purity, advanced pharmaceutical intermediate characterized by its unique difluoro-dimethoxy aniline structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapeutics. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific fluorinated and methoxylated motifs into their molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the biological activity of the difluoroaniline core.
• Material Science: Serves as a monomer or precursor for advanced polymers and functional materials requiring specific electronic properties.
• Organic Synthesis: A versatile reagent for introducing benzyl-protected aniline groups into complex molecules under mild conditions.
• Fluorine Chemistry: Valuable substrate for studying structure-activity relationships (SAR) in fluorinated compound libraries.
• Dye & Pigment Industry: Potential intermediate for creating specialized fluorinated chromophores and photoactive materials.

Basic Information

Product Name	n-Benzyl-2,6-Difluoro-3,5-Dimethoxyaniline
CAS No.	651734-53-1
Molecular Formula	C₁₅H₁₅F₂NO₂
Molecular Weight	279.28 g/mol
Synonyms	2,6-Difluoro-3,5-dimethoxy-N-(phenylmethyl)benzenamine; Benzenamine, 2,6-difluoro-3,5-dimethoxy-N-(phenylmethyl)-; N-Benzyl-2,6-difluoro-3,5-dimethoxyaniline; 2,6-Difluoro-3,5-dimethoxy-N-benzylaniline; N-(Benzyl)-2,6-difluoro-3,5-dimethoxyaniline; 651734-53-1; BDFDMA
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to cGMP principles for the manufacture of pharmaceutical intermediates to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.