Description

6-Bromo-2,3-Difluorobenzenemethanol is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of bromine and fluorine atoms is crucial for modulating biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel, high-value molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoro and bromo substituents enhance lipophilicity and target binding.
• Liquid Crystal Materials: Acts as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Chemical Research & Development: A versatile reagent for academic and industrial research exploring new fluorination methodologies and aromatic chemistry.

Basic Information

Product Name	6-Bromo-2,3-Difluorobenzenemethanol
CAS No.	651326-72-6
Molecular Formula	C7H5BrF2O
Molecular Weight	223.02 g/mol
Synonyms	(6-Bromo-2,3-difluorophenyl)methanol; 2,3-Difluoro-6-bromobenzyl alcohol; 1-(6-Bromo-2,3-difluorophenyl)methanol; Benzenemethanol, 6-bromo-2,3-difluoro-; 6-Bromo-2,3-difluorobenzyl alcohol
EINECS	Contact for details

Quality Control

Our 6-Bromo-2,3-Difluorobenzenemethanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your regulatory needs in cGMP and ISO-compliant environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.