Description

Pyrimidine, 5-(4-Chlorophenyl)-4-Hydrazinyl-6-[4-(Methylsulfonyl)Phenyl]-2-(Trifluoromethyl)- is a high-value, multi-functional heterocyclic compound designed for advanced chemical synthesis. This molecule is engineered to serve as a critical pharmaceutical intermediate and a versatile building block in medicinal chemistry research. It is primarily sought by R&D and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel active ingredients in crop protection and pest management solutions.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.

Basic Information

Product Name	Pyrimidine, 5-(4-Chlorophenyl)-4-Hydrazinyl-6-[4-(Methylsulfonyl)Phenyl]-2-(Trifluoromethyl)-
CAS No.	651315-94-5
Molecular Formula	C18H14ClF3N4O2S
Molecular Weight	442.84 g/mol
Synonyms	5-(4-Chlorophenyl)-4-hydrazinyl-6-[4-(methylsulfonyl)phenyl]-2-(trifluoromethyl)pyrimidine; 4-Hydrazinyl-5-(4-chlorophenyl)-6-[4-(methylsulfonyl)phenyl]-2-(trifluoromethyl)pyrimidine; 2-(Trifluoromethyl)-5-(4-chlorophenyl)-4-hydrozinyl-6-[4-(methylsulfonyl)phenyl]pyrimidine; CAS 651315-94-5; Pyrimidine derivative 651315-94-5; 4-Hydrazino pyrimidine derivative
EINECS	Contact for details

Quality Control

Every batch of this high-purity intermediate is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure consistency and suitability for your critical R&D and scale-up processes. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as per agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.