Description

4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine Sodium Salt is a high-purity, advanced pharmaceutical intermediate with significant commercial and research value. This compound is a critical building block in the synthesis of complex molecules, particularly kinase inhibitors and other targeted therapeutics. It is essential for research and development laboratories, process chemistry teams, and manufacturers in the pharmaceutical and biotechnology sectors seeking reliable, high-quality raw materials for active pharmaceutical ingredient (API) production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drugs targeting various cancers and inflammatory diseases.
• Biochemical Research: Used as a core scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and the development of novel therapeutic agents.
• Process Development: Serves as a critical starting material for scaling up the production of complex active pharmaceutical ingredients (APIs) under cGMP conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific drug candidates and reference standards.

Basic Information

Product Name	4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine Sodium Salt
CAS No.	651035-58-4
Molecular Formula	C6H4ClN4Na
Molecular Weight	190.57 g/mol
Synonyms	2-Amino-4-chloro-7H-pyrrolo[2,3-d]pyrimidine sodium salt; 4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine sodium salt; Sodium 4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-aminide; 4-Chloro-2-amino-7H-pyrrolo[2,3-d]pyrimidine sodium salt; CAS 651035-58-4; Pyrrolopyrimidine sodium salt intermediate
EINECS	Contact for details

Quality Control

Our 4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine Sodium Salt is manufactured under strict quality management systems to ensure batch-to-batch consistency and purity suitable for pharmaceutical research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with ICH guidelines and can provide material for projects requiring documentation traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.