Description

2-[4-[4-(Trifluoromethyl)Pyrimidin-2-Yl]Piperazino]Ethan-1-Ol is a high-value, heterocyclic organic compound featuring a piperazine linker and a trifluoromethyl-substituted pyrimidine core. This structure is critical for its role as a sophisticated pharmaceutical intermediate and research chemical in modern drug discovery programs. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to develop novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging the biological activity of the pyrimidine and piperazine motifs.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and receptor interactions in biological systems.
• Material Science Precursor: Can be utilized in the development of advanced organic materials and ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	2-[4-[4-(Trifluoromethyl)Pyrimidin-2-Yl]Piperazino]Ethan-1-Ol
CAS No.	651004-99-8
Molecular Formula	C11H14F3N4O
Molecular Weight	275.25 g/mol
Synonyms	2-(4-(4-(Trifluoromethyl)pyrimidin-2-yl)piperazin-1-yl)ethanol; 1-(2-Hydroxyethyl)-4-[4-(trifluoromethyl)-2-pyrimidinyl]piperazine; 2-[4-[4-(Trifluoromethyl)-2-pyrimidinyl]-1-piperazinyl]ethanol; 651004-99-8; 2-(4-(4-(Trifluoromethyl)pyrimidin-2-yl)piperazin-1-yl)ethan-1-ol
EINECS	Contact for details

Quality Control

Every batch of 2-[4-[4-(Trifluoromethyl)Pyrimidin-2-Yl]Piperazino]Ethan-1-Ol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.