Description

4-Chloro-1-(4-Methoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidine is a high-purity, heterocyclic organic compound belonging to the pyrazolopyrimidine class, serving as a critical advanced pharmaceutical intermediate. Its molecular structure makes it a valuable synthetic building block for the research and development of novel therapeutic agents, particularly kinase inhibitors. This compound is essential for pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of targeted drug candidates.

Application

• Pharmaceutical Intermediate: Key precursor in the multi-step synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a core scaffold or reference standard in structure-activity relationship (SAR) studies and medicinal chemistry programs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a building block in the development and scale-up of new chemical entities (NCEs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	4-Chloro-1-(4-Methoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	650628-54-9
Molecular Formula	C₁₂H₉ClN₄O
Molecular Weight	260.68 g/mol
Synonyms	4-Chloro-1-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine; 1-(4-Methoxyphenyl)-4-chloro-1H-pyrazolo[3,4-d]pyrimidine; 4-Chloro-1-(p-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine; Pyrazolo[3,4-d]pyrimidine, 4-chloro-1-(4-methoxyphenyl)-; 650628-54-9; 4-Chloro-1-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine, 4-chloro-1-(4-methoxyphenyl)-
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-(4-Methoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical intermediate applications, ensuring reliable supply and traceability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.