Description

2-(Methylthio)-Furo[2,3-D]Pyrimidine-6-Methanol CAS NO 649558-78-1 is a high-purity, advanced pharmaceutical intermediate characterized by its fused furopyrimidine heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, including potential antiviral and anticancer candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting enzyme inhibition.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Antiviral Drug Development: Serves as a core scaffold for researching novel compounds with potential activity against viral pathogens.
• Oncology Research: Employed in the design and synthesis of small-molecule inhibitors for targeted cancer therapies.
• Chemical Biology: Utilized as a probe or labeled compound to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and non-commercial research quantities.

Basic Information

Product Name	2-(Methylthio)-Furo[2,3-D]Pyrimidine-6-Methanol
CAS No.	649558-78-1
Molecular Formula	C9H8N2O2S
Molecular Weight	208.24 g/mol
Synonyms	6-(Hydroxymethyl)-2-(methylthio)furo[2,3-d]pyrimidine; 2-Methylsulfanylfuro[2,3-d]pyrimidine-6-methanol; Furo[2,3-d]pyrimidine-6-methanol, 2-(methylthio)-; 2-(Methylthio)furo[2,3-d]pyrimidin-6-ylmethanol; 649558-78-1; 2-Methylmercaptofuro[2,3-d]pyrimidine-6-methanol
EINECS	Contact for details

Quality Control

Our 2-(Methylthio)-Furo[2,3-D]Pyrimidine-6-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.