Description

6-Fluoro-1H-Indole-3-Carboxylic Acid Methyl Ester is a high-value fluorinated indole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the strategic incorporation of fluorine and the versatile methyl ester functional group, enabling precise molecular modifications for performance enhancement. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and fine-tuning the properties of complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas where fluorinated indole scaffolds are prevalent.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, leveraging the bioactivity of the indole core.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a fluorescent tag or molecular probe due to the indole fluorophore.
• Academic & Contract Research: A valuable reagent for synthetic methodology development and exploratory chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	6-Fluoro-1H-Indole-3-Carboxylic Acid Methyl Ester
CAS No.	649550-97-0
Molecular Formula	C10H8FNO2
Molecular Weight	193.17 g/mol
Synonyms	Methyl 6-Fluoro-1H-indole-3-carboxylate; 6-Fluoroindole-3-carboxylic Acid Methyl Ester; 1H-Indole-3-carboxylic acid, 6-fluoro-, methyl ester; 6-Fluoro-1H-indole-3-carboxylic acid methyl ester; Methyl 6-fluoroindole-3-carboxylate; 6-Fluoroindole-3-methyl carboxylate
EINECS	Contact for details

Quality Control

Every batch of our 6-Fluoro-1H-Indole-3-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.