Description

Ethyl 2-Cyclopropylpyrimidine-5-Carboxylate is a high-purity pyrimidine derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its unique cyclopropyl-substituted pyrimidine core, which enables the construction of complex molecular architectures with specific steric and electronic properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that require a functionalized pyrimidine scaffold.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands, organic semiconductors, and photoactive materials.
• Academic & Contract Research: Essential reagent for method development and exploratory chemistry in university and CRO laboratories.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	Ethyl 2-Cyclopropylpyrimidine-5-Carboxylate
CAS No.	648423-77-2
Molecular Formula	C10H12N2O2
Molecular Weight	192.22 g/mol
Synonyms	Ethyl 2-cyclopropyl-5-pyrimidinecarboxylate; 5-Pyrimidinecarboxylic acid, 2-cyclopropyl-, ethyl ester; 2-Cyclopropylpyrimidine-5-carboxylic acid ethyl ester; Ethyl 2-cyclopropylpyrimidine-5-carboxylate; 648423-77-2; Ethyl 2-cyclopropyl-1,3-diazine-5-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Cyclopropylpyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports applications requiring high standards, including cGMP development and non-GMP research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.