Description

7-Benzyl-4-Chloro-2-(Trifluoromethyl)-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine is a high-value, heterocyclic organic compound featuring a tetrahydropyridopyrimidine core functionalized with benzyl, chloro, and trifluoromethyl groups. This complex molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

This specialized chemical serves as a key synthetic precursor in several high-tech research and development areas:

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Agrochemical Development: Serves as a core structure for creating novel pesticides and herbicides with enhanced efficacy.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and enzyme functions.
• Organic Synthesis Reference Standard: Employed as a pure reference material for analytical method development and validation in QC laboratories.

Basic Information

Product Name	7-Benzyl-4-Chloro-2-(Trifluoromethyl)-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine
CAS No.	647863-01-2
Molecular Formula	C₁₆H₁₃ClF₃N₃
Molecular Weight	339.74 g/mol
Synonyms	7-Benzyl-4-chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine; 4-Chloro-7-benzyl-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine; 5,6,7,8-Tetrahydropyrido[3,4-d]pyrimidine, 7-benzyl-4-chloro-2-(trifluoromethyl)-; 647863-01-2; BCTP; 7-Benzyl-4-chloro-2-trifluoromethyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to stringent quality protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality management system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.