Description

Dermaseptin Tfa CAS NO 646451-06-1 is a synthetic antimicrobial peptide (AMP) derived from frog skin secretions, provided as a trifluoroacetate (TFA) salt. This compound is of significant interest for its broad-spectrum activity against bacteria, fungi, and protozoa, making it a valuable research tool for studying host defense mechanisms and developing novel therapeutic agents. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for antimicrobial research, peptide-based drug discovery, and the development of new anti-infective formulations.

Application

• Antimicrobial Research: Used as a reference standard and active agent in studies investigating mechanisms of action against Gram-positive and Gram-negative bacteria, fungi, and parasites.
• Drug Discovery & Development: Serves as a lead compound or template for the design and synthesis of novel peptide-based antibiotics and anti-infective agents.
• Biomaterial Coating: Explored for coating medical devices and implants to prevent biofilm formation and microbial colonization.
• Cosmeceutical Research: Investigated for potential applications in topical formulations for skin care due to its antimicrobial and possible wound-healing properties.
• Veterinary Pharmaceutical Development: Studied for use in animal health products to combat infectious diseases.
• Academic & Institutional Research: Employed in university and government laboratories for fundamental research in immunology, peptide chemistry, and microbiology.

Basic Information

Product Name	Dermaseptin Tfa
CAS No.	646451-06-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Dermaseptin Trifluoroacetate; Dermaseptin TFA Salt; Antimicrobial Peptide Dermaseptin; Dermaseptin (TFA); DRS TFA; Frog Skin Antimicrobial Peptide TFA
EINECS	Contact for details

Quality Control

Our Dermaseptin Tfa is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and MS for identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and other critical parameters is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.