Description

Fmoc-β-Homocys(Trt)-Oh is a protected, non-proteinogenic amino acid derivative specifically engineered for solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring precise control over peptide chain assembly, particularly for the incorporation of homocysteine analogs. It is an essential building block for pharmaceutical R&D, enabling the synthesis of complex peptides and peptidomimetics with potential therapeutic applications in metabolic and cardiovascular research.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected building block for the automated synthesis of custom peptides.
• Pharmaceutical Research & Development: Used in the discovery and development of novel peptide-based drugs and bioactive compounds.
• Peptidomimetic Design: Facilitates the creation of stable peptide analogs by incorporating homocysteine derivatives into molecular scaffolds.
• Bioconjugation and Labeling: Serves as a precursor for introducing functional handles or labels into peptides via the thiol group after deprotection.
• Academic and Institutional Research: Employed in biochemical studies investigating protein structure, function, and protein-protein interactions.
• Production of Reference Standards: Used to synthesize high-purity peptide standards for analytical method development and quality control.

Basic Information

Product Name	Fmoc-β-Homocys(Trt)-Oh
CAS No.	646068-80-6
Molecular Formula	C41H37NO4S
Molecular Weight	639.80 g/mol
Synonyms	Fmoc-β-homocysteine(Trt)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-β-homocysteine; Fmoc-Hcy(Trt)-OH; Fmoc-β-Hcy(Trt)-OH; (2R)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-4-(tritylsulfanyl)butanoic acid; Fmoc-L-β-homocysteine(Trt)-OH; Fmoc-β-homo-Cys(Trt)-OH; Fmoc-β-HomoCys(Trt)-OH
EINECS	Contact for details

Quality Control

Our Fmoc-β-Homocys(Trt)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.