Description

6-Fluoro-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one is a high-purity, fluorinated heterocyclic compound serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique fused quinazolinone-pyrrolidine structure, which is essential for synthesizing novel bioactive molecules targeting specific therapeutic pathways. This product is primarily needed by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Kinase Inhibitor Development: Used in the research and development of small-molecule kinase inhibitors for targeted cancer therapies.
• Chemical Biology Probes: Serves as a core scaffold for creating molecular probes to study enzyme function and biological pathways.
• Organic Synthesis Research: Employed in academic and industrial R&D for constructing complex heterocyclic systems and exploring new synthetic methodologies.
• Preclinical Drug Development: Utilized in the synthesis of compounds for pharmacological screening and early-stage preclinical studies.

Basic Information

Product Name	6-Fluoro-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one
CAS No.	642491-84-7
Molecular Formula	C₁₁H₉FN₂O
Molecular Weight	204.20 g/mol
Synonyms	6-Fluoro-1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-9-one; 6-Fluoro-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one; 6-Fluoro-1H,2H,3H,9H-pyrrolo[2,1-b]quinazolin-9-one; 6-Fluoro-2,3-dihydro-pyrrolo[2,1-b]quinazolin-9(1H)-one; 642491-84-7; 6-Fluoro-2,3-dihydropyrrolo[2,1-b]quinazolin-9-one
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.