Description

5-Fluoro-2-(4-Methoxyphenoxy)Phenylamine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct aromatic ether and amine functional groups. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug molecules, especially those targeting central nervous system (CNS) disorders and inflammatory conditions.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its fluorinated phenoxy structure.
• Material Science: Acts as a monomer or functionalizing agent in the production of specialty polymers and advanced organic materials.
• Organic Synthesis: Employed in cross-coupling reactions and as a building block for complex heterocyclic compounds in academic and industrial R&D.
• Ligand Preparation: Utilized in the preparation of specialized ligands for catalytic systems and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Fluoro-2-(4-Methoxyphenoxy)Phenylamine
CAS No.	640767-08-4
Molecular Formula	C13H12FNO2
Molecular Weight	233.24 g/mol
Synonyms	5-Fluoro-2-(4-methoxyphenoxy)aniline; 2-Amino-5-fluoro-4'-methoxydiphenyl ether; Benzenamine, 5-fluoro-2-(4-methoxyphenoxy)-; 4'-Methoxy-5-fluoro-2-aminodiphenyl ether; 5-Fluoro-2-(p-methoxyphenoxy)aniline; 640767-08-4; 5-Fluoro-2-(4-methoxyphenoxy)phenylamine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(4-Methoxyphenoxy)Phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to minimize contact with moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.