Description

4,6-Dichloro-2-(4-Fluorophenyl)-5-Nitropyrimidine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its versatile reactivity, offering distinct sites for nucleophilic aromatic substitution and functional group transformations, which is critical for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, particularly as a key intermediate in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its pyrimidine core.
• Material Science: Acts as a building block for creating specialized polymers, liquid crystals, or organic electronic materials.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and exploring novel chemical reactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring specific, high-purity nitropyrimidine derivatives.

Basic Information

Product Name	4,6-Dichloro-2-(4-Fluorophenyl)-5-Nitropyrimidine
CAS No.	640271-57-4
Molecular Formula	C10H4Cl2FN3O2
Molecular Weight	288.06 g/mol
Synonyms	2-(4-Fluorophenyl)-4,6-dichloro-5-nitropyrimidine; 4,6-Dichloro-2-(4-fluorophenyl)-5-nitropyrimidine; 5-Nitro-4,6-dichloro-2-(4-fluorophenyl)pyrimidine; 4,6-Dichloro-5-nitro-2-(p-fluorophenyl)pyrimidine; 2-(p-Fluorophenyl)-4,6-dichloro-5-nitropyrimidine; 4,6-Dichloro-2-(4'-fluorophenyl)-5-nitropyrimidine; CAS 640271-57-4
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-2-(4-Fluorophenyl)-5-Nitropyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain integrity and traceability ensures reliable material for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.