Description

2-(4-Fluorophenyl)-6-Hydroxy-5-Nitro-4(3H)-Pyrimidinone is a specialized pyrimidinone derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fluorinated and nitrated structure enables precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors engaged in the synthesis of complex, high-value molecules.

Application

• Critical intermediate in the research and development of novel pharmaceutical compounds, particularly kinase inhibitors and antiviral agents.
• Key building block for the synthesis of advanced agrochemicals, including herbicides and fungicides.
• Versatile precursor in fine chemical synthesis for creating complex heterocyclic scaffolds.
• Used in academic and industrial research for structure-activity relationship (SAR) studies.
• Intermediate in the production of dyes and specialty pigments.
• Starting material for the development of chemical probes and diagnostic reagents.

Basic Information

Product Name	2-(4-Fluorophenyl)-6-Hydroxy-5-Nitro-4(3H)-Pyrimidinone
CAS No.	640271-56-3
Molecular Formula	C10H6FN3O4
Molecular Weight	251.17 g/mol
Synonyms	5-Nitro-6-hydroxy-2-(4-fluorophenyl)-4(3H)-pyrimidinone; 2-(4-Fluorophenyl)-5-nitro-6-hydroxy-4(3H)-pyrimidinone; 4(3H)-Pyrimidinone, 2-(4-fluorophenyl)-6-hydroxy-5-nitro-; 640271-56-3; 2-(p-Fluorophenyl)-6-hydroxy-5-nitro-4(3H)-pyrimidinone; 6-Hydroxy-2-(4-fluorophenyl)-5-nitro-4(3H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)-6-Hydroxy-5-Nitro-4(3H)-Pyrimidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.