Description

6-Amino-1-(Tetrahydro-Furan-2-Ylmethyl)-1H-Pyrimidine-2,4-Dione is a high-purity pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and building block for the development of novel active ingredients. It is primarily required by research institutions and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs and other active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Research: Potential application in the study of enzyme inhibitors and nucleotide-related biochemical pathways.
• Fine Chemical Synthesis: Serves as a specialized building block for creating complex heterocyclic compounds with tailored properties.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations for cGMP production of clinical trial materials.

Basic Information

Product Name	6-Amino-1-(Tetrahydro-Furan-2-Ylmethyl)-1H-Pyrimidine-2,4-Dione
CAS No.	638136-91-1
Molecular Formula	C9H13N3O3
Molecular Weight	211.22 g/mol
Synonyms	6-Amino-1-(tetrahydrofuran-2-ylmethyl)pyrimidine-2,4(1H,3H)-dione; 6-Amino-1-(tetrahydro-2-furanylmethyl)-1H-pyrimidine-2,4-dione; 1-(Tetrahydrofuran-2-ylmethyl)-6-aminouracil; 6-Amino-1-(tetrahydrofuran-2-ylmethyl)uracil; 6-Amino-1-(THF-2-ylmethyl)uracil; 638136-91-1; 6-Amino-1-(tetrahydrofuran-2-ylmethyl)-2,4(1H,3H)-pyrimidinedione
EINECS	Contact for details

Quality Control

Our 6-Amino-1-(Tetrahydro-Furan-2-Ylmethyl)-1H-Pyrimidine-2,4-Dione is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliance for pharmaceutical applications and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.