Description

1-(3-Formyl-9-Methyl-4-Oxo-4H-Pyrido[1,2-A]Pyrimidin-2-Yl)-Piperidine-4-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by research institutions, custom synthesis laboratories, and pharmaceutical companies engaged in the development of new chemical entities and complex generic drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of target drug molecules, especially those with fused pyrido-pyrimidine cores.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Employed in the process development and scale-up of new active pharmaceutical ingredients, enabling route scouting and optimization.
• Custom Synthesis: Supplied to contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring specialized heterocyclic chemistry.
• Chemical Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	1-(3-Formyl-9-Methyl-4-Oxo-4H-Pyrido[1,2-A]Pyrimidin-2-Yl)-Piperidine-4-Carboxylic Acid Ethyl Ester
CAS No.	636989-80-5
Molecular Formula	C19H21N3O5
Molecular Weight	371.39 g/mol
Synonyms	Ethyl 1-(3-formyl-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)piperidine-4-carboxylate; 1-(3-Formyl-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)piperidine-4-carboxylic acid ethyl ester; 636989-80-5; UNII-8J0Z50S4Q8; 8J0Z50S4Q8; SCHEMBL218090; AKOS040759246; AS-76333; ZINC000253909996
EINECS	Contact for details

Quality Control

Our 1-(3-Formyl-9-Methyl-4-Oxo-4H-Pyrido[1,2-A]Pyrimidin-2-Yl)-Piperidine-4-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) documenting full specifications are available upon request to support your quality and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.