Description

5H-Pyrimido[4,5-D]Azepine, 2,4-Dichloro-6,7,8,9-Tetrahydro-7-(Phenylmethyl)- is a high-purity, advanced pharmaceutical intermediate (API intermediate) characterized by its complex fused heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, oncology, or other therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis: Serves as a versatile precursor for further chemical modifications, including cross-coupling reactions and functional group transformations.
• Biochemical Research: Potential use as a tool compound or inhibitor in biochemical assays to study specific enzyme or receptor pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for advanced applications.

Basic Information

Product Name	5H-Pyrimido[4,5-D]Azepine, 2,4-Dichloro-6,7,8,9-Tetrahydro-7-(Phenylmethyl)-
CAS No.	635698-48-5
Molecular Formula	C17H15Cl2N3
Molecular Weight	332.23 g/mol
Synonyms	2,4-Dichloro-7-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine; 7-Benzyl-2,4-dichloro-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine; 2,4-Dichloro-7-(phenylmethyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine; 5H-Pyrimido[4,5-d]azepine, 2,4-dichloro-6,7,8,9-tetrahydro-7-(phenylmethyl)-; CAS 635698-48-5
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Every lot is analyzed using modern analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Single Maximum Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.