Description

2,4-Dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride is a high-purity, heterocyclic building block of significant importance in modern pharmaceutical and agrochemical research. Its core value lies in its functionalized pyridopyrimidine scaffold, which serves as a versatile intermediate for the synthesis of complex bioactive molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic core structure.
• Chemical Biology & Proteomics: Serves as a valuable scaffold for creating chemical probes and tool compounds to study enzyme function and biological pathways.
• Process Chemistry & Scale-up: Employed in route scouting, optimization, and the production of kilogram-scale batches for preclinical and clinical studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals for clients.
• Academic Research: Utilized in university and institutional laboratories for methodological development in organic synthesis and medicinal chemistry projects.

Basic Information

Product Name	2,4-Dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride
CAS No.	635698-30-5
Molecular Formula	C7H8Cl3N3
Molecular Weight	248.52 g/mol
Synonyms	2,4-Dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine HCl; 2,4-Dichloro-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine hydrochloride; 5,6,7,8-Tetrahydro-2,4-dichloropyrido[4,3-d]pyrimidine hydrochloride; Pyrido[4,3-d]pyrimidine, 2,4-dichloro-5,6,7,8-tetrahydro-, hydrochloride; 635698-30-5; 2,4-Dichloro-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine hydrochloride
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including GMP-grade upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.