Description

Pro-Gly-Ome Tfa is a specialized, high-purity chemical building block used in advanced pharmaceutical research and development. This compound is critical for the synthesis of complex peptides and peptidomimetics, offering researchers precise control over molecular structure and function. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical, biotechnology, and academic sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and metabolic disease research.
• Peptide Chemistry: Used for the solid-phase and solution-phase synthesis of complex peptides and modified peptide sequences.
• Protease Inhibitor Development: Serves as a core scaffold or precursor in the design of enzyme inhibitors targeting specific proteolytic pathways.
• Bioconjugation: Facilitates the site-specific modification of proteins and antibodies for drug delivery and diagnostic applications.
• Chemical Biology Probes: Employed in the creation of activity-based probes to study enzyme function and mechanism in biological systems.
• Academic & Institutional Research: Supports fundamental research in medicinal chemistry, biochemistry, and molecular biology at universities and research institutes.

Basic Information

Product Name	Pro-Gly-Ome Tfa
CAS No.	634922-10-4
Molecular Formula	C9H12F3N3O5
Molecular Weight	299.21 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-prolylglycine 2,2,2-Trifluoroethyl Ester; Fmoc-Pro-Gly-OCH2CF3; Fmoc-Pro-Gly-O-Tfe; Fmoc-L-Prolyl-Glycine 2,2,2-Trifluoroethyl Ester; (2S)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-pyrrolidinecarboxylic Acid (2,2,2-Trifluoroethyl) Ester; Pro-Gly-O-Tfa-Fmoc; Fmoc-Pro-Gly-OCH2CF3 Ester
EINECS	Contact for details

Quality Control

Our Pro-Gly-Ome Tfa is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and pharmaceutical intermediates, with specifications tailored to meet the rigorous demands of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.