Description

N~1~-(1-Phenylethyl)-4-(Trifluoromethyl)Benzene-1,2-Diamine is a high-purity, advanced pharmaceutical intermediate featuring a unique diamine structure with a trifluoromethyl substituent. This compound is valued for its role as a critical building block in the synthesis of complex molecules, particularly in medicinal chemistry where the trifluoromethyl group is a key pharmacophore. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and cancer.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the bioactivity of the trifluoromethyl-diamine moiety.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialized polymers and advanced functional materials.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and fine chemicals.
• Ligand Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis, given its potential for stereogenic centers.

Basic Information

Product Name	N~1~-(1-Phenylethyl)-4-(Trifluoromethyl)Benzene-1,2-Diamine
CAS No.	634176-88-8
Molecular Formula	C15H15F3N2
Molecular Weight	280.29 g/mol
Synonyms	1,2-Benzenediamine, N1-(1-phenylethyl)-4-(trifluoromethyl)-; 4-(Trifluoromethyl)-N1-(1-phenylethyl)-1,2-benzenediamine; N1-(α-Methylbenzyl)-4-(trifluoromethyl)-1,2-phenylenediamine; (1-Phenylethyl)-[4-(trifluoromethyl)-1,2-phenylenediamine]; 634176-88-8; 4-CF3-N1-(1-phenylethyl)benzene-1,2-diamine
EINECS	Contact for details

Quality Control

Our N~1~-(1-Phenylethyl)-4-(Trifluoromethyl)Benzene-1,2-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.