Description

5-Bromo-2-Chloro-4-Methylpyrimidine is a high-purity halogenated pyrimidine building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer therapies. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of nucleoside analogs and other small molecule drugs targeting viral and oncological diseases.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging its halogenated pyrimidine core.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce functionalized pyrimidine rings into more complex molecules.
• Material Science Precursor: Serves as a starting material for creating ligands in catalysis or functional monomers for advanced polymers.
• Academic & R&D: Utilized in research laboratories for methodological development and exploring new chemical entities.

Basic Information

Product Name	5-Bromo-2-Chloro-4-Methylpyrimidine
CAS No.	633328-95-7
Molecular Formula	C5H4BrClN2
Molecular Weight	207.45 g/mol
Synonyms	2-Chloro-5-bromo-4-methylpyrimidine; 4-Methyl-5-bromo-2-chloropyrimidine; 5-Bromo-2-chloro-4-methyl-pyrimidine; 633328-95-7; Pyrimidine, 5-bromo-2-chloro-4-methyl-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-4-Methylpyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.