Description

3-Bromo-4-Fluorobenzenesulfonyl Chloride is a high-purity organosulfur compound that serves as a versatile and critical building block in advanced chemical synthesis. Its value lies in its dual functionality as both an electrophilic sulfonylating agent and a halogenated aromatic scaffold, enabling the precise construction of complex molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality reagents for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used to construct novel herbicide and pesticide molecules, leveraging the sulfonyl chloride group for bioactivity.
• Material Science: Building block for creating specialty polymers and advanced organic electronic materials due to its halogen and sulfonyl functionalities.
• Chemical Research: Essential reagent in medicinal chemistry and process development for introducing the 3-bromo-4-fluorophenylsulfonyl moiety.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing tailored compounds for clients.

Basic Information

Product Name	3-Bromo-4-Fluorobenzenesulfonyl Chloride
CAS No.	631912-19-1
Molecular Formula	C6H3BrClFO2S
Molecular Weight	273.51 g/mol
Synonyms	3-Bromo-4-fluorobenzenesulfonyl chloride; 4-Fluoro-3-bromobenzenesulfonyl chloride; 1-Bromo-2-fluoro-4-(chlorosulfonyl)benzene; Benzenesulfonyl chloride, 3-bromo-4-fluoro-; 3-Bromo-4-fluorophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Fluorobenzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.