Description

(4-Chloro-2-Pyrimidinyl)Carbamic Acid 1,1-Dimethylethyl Ester is a high-purity pyrimidine derivative, a crucial protected intermediate in advanced organic synthesis. Its primary value lies in enabling the controlled introduction of the 4-chloro-2-aminopyrimidine pharmacophore, a key structural motif in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of small molecule drugs, especially protein kinase inhibitors.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology: Serves as a versatile scaffold for creating probes and tool compounds to study biological pathways.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for client-specific molecule development.
• Academic Research: Utilized in university and institutional labs for methodological development and novel heterocyclic chemistry.

Basic Information

Product Name	(4-Chloro-2-Pyrimidinyl)Carbamic Acid 1,1-Dimethylethyl Ester
CAS No.	629645-55-2
Molecular Formula	C9H12ClN3O2
Molecular Weight	229.66 g/mol
Synonyms	tert-Butyl (4-chloropyrimidin-2-yl)carbamate; N-Boc-4-chloro-2-aminopyrimidine; 4-Chloro-2-((tert-butoxycarbonyl)amino)pyrimidine; Boc-4-chloro-2-aminopyrimidine; 2-((tert-Butoxycarbonyl)amino)-4-chloropyrimidine; 4-Chloro-2-pyrimidinamine, N-[(1,1-dimethylethoxy)carbonyl]-; (4-Chloro-pyrimidin-2-yl)-carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our (4-Chloro-2-Pyrimidinyl)Carbamic Acid 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.