Description

tert-Butyl (4-Hydroxypyrimidin-2-Yl)Carbamate is a high-purity chemical building block and protected intermediate of significant value in advanced organic synthesis. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and fine chemicals, particularly within the pyrimidine class. Its primary utility lies in the controlled introduction of the 4-hydroxypyrimidin-2-yl moiety into complex molecular architectures, making it a critical material for pharmaceutical R&D and process chemistry.

Application

• Pharmaceutical Intermediate: A key protected synthon in the research and development of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the pyrimidine core provides specific biological activity.
• Chemical Research & Development: Serves as a versatile building block for constructing complex heterocyclic compounds in academic and industrial laboratories.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for the production of high-value fine chemicals.
• Material Science Precursor: Potential use in the synthesis of organic ligands and functional molecules for advanced materials.

Basic Information

Product Name	tert-Butyl (4-Hydroxypyrimidin-2-Yl)Carbamate
CAS No.	629645-53-0
Molecular Formula	C9H13N3O3
Molecular Weight	211.22 g/mol
Synonyms	2-(((tert-Butoxy)carbonyl)amino)-4-hydroxypyrimidine; tert-Butyl N-(4-hydroxypyrimidin-2-yl)carbamate; 2-((tert-Butoxycarbonyl)amino)pyrimidin-4-ol; Boc-4-hydroxypyrimidin-2-ylamine; (4-Hydroxypyrimidin-2-yl)carbamic acid tert-butyl ester; 2-(Boc-amino)-4-hydroxypyrimidine; 4-Hydroxy-2-pyrimidinamine, N-Boc derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl (4-Hydroxypyrimidin-2-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use and can supply grades aligned with cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.