Description

4-Bromo-2,3-difluoro-6-nitroaniline is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and nitro substituents, makes it an essential intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides where the difluoro and nitro groups contribute to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Intermediate for producing complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: Valuable substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine atom.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and discovery chemistry projects.

Basic Information

Product Name	4-Bromo-2,3-difluoro-6-nitroaniline
CAS No.	626238-73-1
Molecular Formula	C6H3BrF2N2O2
Molecular Weight	252.99 g/mol
Synonyms	2,3-Difluoro-4-bromo-6-nitroaniline; 4-Bromo-2,3-difluoro-6-nitrobenzenamine; 6-Amino-3-bromo-2,4-difluoronitrobenzene; Benzenamine, 4-bromo-2,3-difluoro-6-nitro-; 4-Bromo-2,3-difluoro-6-nitro-phenylamine; 626238-73-1 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,3-difluoro-6-nitroaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.