Description

Imidazo[1,2-B][1,2,4]Triazine-3(4H)-Thione, 6-Ethoxy-6,7-Dihydro-7-Hydroxy-, (6R,7R)-Rel- (9Ci) is a high-purity, stereochemically defined heterocyclic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its complex fused-ring structure and specific stereochemistry make it a valuable building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and the synthesis of complex target molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new therapeutic agents, particularly in antiviral, anticancer, and anti-inflammatory drug candidates.
• Agrochemical Research: Used as a precursor in the synthesis of novel pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex nitrogen-containing heterocycles due to its reactive thione and hydroxy functional groups.
• Process Chemistry: Serves as a standardized intermediate in scale-up and optimization studies for the production of fine chemicals under Good Manufacturing Practice (GMP) conditions.
• Material Science Research: Potential precursor for the development of specialty polymers or ligands with specific electronic or coordination properties.

Basic Information

Product Name	Imidazo[1,2-B][1,2,4]Triazine-3(4H)-Thione, 6-Ethoxy-6,7-Dihydro-7-Hydroxy-, (6R,7R)-Rel- (9Ci)
CAS No.	625395-85-9
Molecular Formula	C7H9N3O2S
Molecular Weight	199.23 g/mol
Synonyms	rel-(6R,7R)-6-Ethoxy-6,7-dihydro-7-hydroxyimidazo[1,2-b][1,2,4]triazine-3(4H)-thione; (6R,7R)-6-Ethoxy-7-hydroxy-4,6,7,8-tetrahydroimidazo[1,2-b][1,2,4]triazine-3-thione; 6-Ethoxy-7-hydroxy-4,6,7,8-tetrahydroimidazo[1,2-b][1,2,4]triazine-3-thione; CAS 625395-85-9; Imidazo[1,2-b][1,2,4]triazine-3(4H)-thione, 6-ethoxy-6,7-dihydro-7-hydroxy-, (6R,7R)-rel-
EINECS	Contact for details

Quality Control

Our production of Imidazo[1,2-B][1,2,4]Triazine-3(4H)-Thione, 6-Ethoxy-6,7-Dihydro-7-Hydroxy-, (6R,7R)-Rel- (9Ci) adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, chiral purity, and chemical purity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment. We support development under quality guidelines appropriate for its use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.