Description

5H-Pyrimido[4,5-B]Azepin-5-One,2-Ethyl-6,7,8,9-Tetrahydro-9-Methyl-(9Ci) is a high-purity, advanced pharmaceutical intermediate belonging to a class of fused heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and oncological targets.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of proprietary drug candidates and novel chemical entities.
• Drug Discovery Research: Serves as a core scaffold for medicinal chemistry programs, enabling the exploration of structure-activity relationships (SAR) in new therapeutic areas.
• Process Chemistry Development: Used in the optimization and scale-up of synthetic routes for potential APIs under Good Manufacturing Practice (GMP) conditions.
• Academic & Contract Research: Employed in university laboratories and CROs (Contract Research Organizations) for fundamental organic chemistry research and custom synthesis projects.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	5H-Pyrimido[4,5-B]Azepin-5-One,2-Ethyl-6,7,8,9-Tetrahydro-9-Methyl-(9Ci)
CAS No.	625106-67-4
Molecular Formula	C11H15N3O
Molecular Weight	205.26 g/mol
Synonyms	2-Ethyl-6,7,8,9-tetrahydro-9-methyl-5H-pyrimido[4,5-b]azepin-5-one; 2-Ethyl-9-methyl-5,6,7,8-tetrahydro-5H-pyrimido[4,5-b]azepin-5-one; 5H-Pyrimido[4,5-b]azepin-5-one, 2-ethyl-6,7,8,9-tetrahydro-9-methyl-; 625106-67-4; 9-Methyl-2-ethyl-5,6,7,8-tetrahydro-5H-pyrimido[4,5-b]azepin-5-one
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and purity suitable for research and development applications. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.