Description

2-Methyl-5-(Pentafluorosulfur)Aniline is a specialized fluorinated aniline derivative, distinguished by the presence of a pentafluorosulfur (SF5) functional group. This unique structure imparts high chemical and thermal stability, making it a valuable building block for advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for synthesizing novel compounds with enhanced properties. The compound, identified by CAS number 623943-52-2, is a key intermediate for innovators requiring high-purity, functionalized aromatic amines.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those requiring the unique lipophilicity and metabolic stability conferred by the SF5 group.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, where the SF5 moiety can enhance biological activity and environmental persistence.
• Advanced Material Precursor: Serves as a monomer or functionalizing agent in the production of specialty polymers, liquid crystals, and electronic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, leveraging the strong electron-withdrawing nature of the SF5 group.
• Fluorinated Compound Library: A key reagent for medicinal and combinatorial chemists building diverse screening libraries focused on fluorinated compounds.
• Dye and Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	2-Methyl-5-(Pentafluorosulfur)Aniline
CAS No.	623943-52-2
Molecular Formula	C7H6F5NS
Molecular Weight	231.19 g/mol
Synonyms	5-(Pentafluoro-λ6-sulfanyl)-2-methylaniline; 2-Methyl-5-(pentafluorosulfanyl)aniline; 2-Methyl-5-SF5-Aniline; Benzenamine, 2-methyl-5-(pentafluorosulfanyl)-; 2-Methyl-5-(pentafluorosulphanyl)aniline; 5-(Pentafluorosulfur)-2-methylaniline; 2-Methyl-5-(SF5)aniline
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-5-(Pentafluorosulfur)Aniline is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the precise requirements for research and scale-up applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity (by NMR and IR), and impurity profile. Our quality commitment ensures reliability for your critical synthetic pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.