Description

Zabofloxacin CAS NO 623574-00-5 is a novel, broad-spectrum fluoroquinolone antibiotic belonging to the fourth generation of this important pharmaceutical class. It is valued for its potent activity against a wide range of Gram-positive and Gram-negative bacteria, including drug-resistant strains. This compound is essential for pharmaceutical R&D and manufacturing, particularly in the development of new antibacterial agents to address the growing challenge of antimicrobial resistance.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of novel antibacterial drugs and clinical trial materials.
• Antimicrobial Research: A key reference standard and investigational compound in microbiology and pharmacology laboratories.
• Veterinary Medicine Development: Research into applications for treating bacterial infections in animals.
• Mechanism of Action Studies: Used in biochemical research to study bacterial DNA gyrase and topoisomerase IV inhibition.
• Comparative Efficacy Testing: Benchmarking against other fluoroquinolones in in-vitro and in-vivo studies.
• Drug Combination Research: Investigation of synergistic effects with other antibiotic classes.

Basic Information

Product Name	Zabofloxacin
CAS No.	623574-00-5
Molecular Formula	C19H21FN4O4
Molecular Weight	388.39 g/mol
Synonyms	DW-224a; Zabofloxacin hydrochloride; (3S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid; DW224a; NSC-754041; AVE-6971
EINECS	Contact for details

Quality Control

Our Zabofloxacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity and related substances, identity confirmation by spectroscopic methods, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.