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2',3',5'-Tri-o-Benzoyl-2'--C-Methyl-6-Azauridine CAS NO 622379-83-3


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CAS No.:622379-83-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2',3',5'-Tri-o-Benzoyl-2'--C-Methyl-6-Azauridine is a key protected nucleoside derivative, specifically engineered for advanced pharmaceutical synthesis and research. This compound serves as a critical synthetic intermediate, offering a protected scaffold that enables precise chemical modifications in the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of nucleoside-based drugs, antiviral agents, and other high-value fine chemicals.

Application

  • Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel nucleoside analogs and prodrugs.
  • Antiviral Drug Research: Used in the research and development of potential antiviral compounds targeting a range of viral pathogens.
  • Medicinal Chemistry: Serves as a protected precursor for structure-activity relationship (SAR) studies and lead optimization.
  • Biochemical Research: Employed in studies investigating nucleoside metabolism, enzyme inhibition, and cellular signaling pathways.
  • Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for specialized chemical entities.
  • Academic Research: A valuable reagent for universities and research institutes exploring nucleic acid chemistry and drug discovery.

Basic Information

Product Name 2',3',5'-Tri-o-Benzoyl-2'--C-Methyl-6-Azauridine
CAS No. 622379-83-3
Molecular Formula C31H26N2O8
Molecular Weight 554.55 g/mol
Synonyms 2'-C-Methyl-2',3',5'-tri-O-benzoyl-6-azauridine; 6-Aza-2'-C-methyluridine 2',3',5'-tribenzoate; 1-((2R,3R,4R,5R)-3,4-Bis(benzoyloxy)-5-((benzoyloxy)methyl)-3-methyltetrahydrofuran-2-yl)-1,2,4-triazine-3,5(2H,4H)-dione; 2',3',5'-Tri-O-benzoyl-2'-C-methyl-6-azauridine; Protected 6-Azauridine Derivative; Benzoylated C-Methyl Azanucleoside
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Quality Control

Our 2',3',5'-Tri-o-Benzoyl-2'--C-Methyl-6-Azauridine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment; consider storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%
Single Unknown Impurity (HPLC) ≤ 1.0%
Total Impurities (HPLC) ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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