Description

α-[[2-(4-Fluorophenoxy)-9-Methyl-4-Oxo-4H-Pyrido[1,2-A]Pyrimidin-3-Yl]Methylene]-2-Benzothiazoleacetonitrile is a high-value, complex heterocyclic compound that serves as a critical advanced intermediate in modern organic synthesis. Its intricate molecular architecture, featuring fused pyrido[1,2-a]pyrimidinone and benzothiazole moieties, makes it a versatile building block for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets, anti-infectives, or oncology research due to its privileged heterocyclic scaffold.
• Agrochemical Research: Used as a building block for developing new generation pesticides, herbicides, or fungicides with enhanced efficacy and selectivity.
• Material Science: Potential intermediate for creating organic semiconductors, liquid crystals, or fluorescent dyes owing to its extended π-conjugated system.
• Chemical Biology Probe Development: Serves as a core structure for designing molecular probes to study enzyme function or cellular pathways.
• Academic & Contract Research: Essential for synthetic methodology development and exploring new chemical spaces in university and CRO (Contract Research Organization) laboratories.
• Custom Synthesis & Scale-Up: Supplied to fine chemical manufacturers for custom synthesis projects and process development for client-specific molecules.

Basic Information

Product Name	α-[[2-(4-Fluorophenoxy)-9-Methyl-4-Oxo-4H-Pyrido[1,2-A]Pyrimidin-3-Yl]Methylene]-2-Benzothiazoleacetonitrile
CAS No.	620113-73-7
Molecular Formula	C27H17FN4O2S
Molecular Weight	480.52 g/mol
Synonyms	2-Benzothiazoleacetonitrile, α-[[2-(4-fluorophenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]methylene]-; (Z)-2-((2-(4-Fluorophenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)methylene)benzo[d]thiazole-3(2H)-acetonitrile; 620113-73-7; 9-Methyl-3-[(2-benzothiazol-2-yl-1-cyanoethenyl)]-2-(4-fluorophenoxy)-4H-pyrido[1,2-a]pyrimidin-4-one
EINECS	Contact for details

Quality Control

Every batch of α-[[2-(4-Fluorophenoxy)-9-Methyl-4-Oxo-4H-Pyrido[1,2-A]Pyrimidin-3-Yl]Methylene]-2-Benzothiazoleacetonitrile is manufactured and controlled under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, which is critical for your research and development continuity. A detailed Certificate of Analysis (COA) is supplied with each shipment, typically including results from HPLC, NMR, and MS analyses. Our quality commitment supports compliance with ISO standards and the rigorous demands of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.