Description

6-Amino-2,3-Dihydro-1-[(Tetrahydro-2-Furanyl)Methyl]-2-Thioxo-4(1H)-Pyrimidinone CAS NO 618913-50-1 is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrimidinone-thioxo core structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the final or penultimate steps for constructing complex molecules with potential antiviral or neurological activity.
• Biochemical Research: Employed in the study of enzyme inhibition and receptor binding assays due to its specific heterocyclic structure.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	6-Amino-2,3-Dihydro-1-[(Tetrahydro-2-Furanyl)Methyl]-2-Thioxo-4(1H)-Pyrimidinone
CAS No.	618913-50-1
Molecular Formula	C9H13N3O2S
Molecular Weight	227.28 g/mol
Synonyms	6-Amino-1-(tetrahydrofuran-2-ylmethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 6-Amino-1-((tetrahydro-2-furanyl)methyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone; 1-(Tetrahydrofuran-2-ylmethyl)-6-amino-2-thioxo-1,2-dihydropyrimidin-4-one; 6-Amino-2-thioxo-1-(tetrahydrofuran-2-ylmethyl)-1,2-dihydropyrimidin-4-one; 4(1H)-Pyrimidinone, 6-amino-2,3-dihydro-1-[(tetrahydro-2-furanyl)methyl]-2-thioxo-; CAS 618913-50-1
EINECS	Contact for details

Quality Control

Our 6-Amino-2,3-Dihydro-1-[(Tetrahydro-2-Furanyl)Methyl]-2-Thioxo-4(1H)-Pyrimidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.