Description

1-(2,4-Difluorophenyl)-3-(4-Fluorophenyl)-1H-Pyrazole-4-Carbaldehyde is a high-purity fluorinated pyrazole derivative, a critical advanced intermediate in modern synthetic chemistry. Its value lies in its precise molecular architecture, which serves as a versatile building block for constructing complex, biologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating new active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and anti-infectives.
• Agrochemical Synthesis: Serves as a core scaffold for developing new-generation herbicides, fungicides, and insecticides, leveraging the stability and bioactivity imparted by the fluorine atoms.
• Material Science Research: Used in the development of specialty chemicals, organic light-emitting diodes (OLEDs), and advanced polymers where fluorinated aromatic systems are required.
• Chemical Biology & Proteomics: Acts as a reactive handle or linker in the design of chemical probes and activity-based protein profiling (ABPP) agents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	1-(2,4-Difluorophenyl)-3-(4-Fluorophenyl)-1H-Pyrazole-4-Carbaldehyde
CAS No.	618098-78-5
Molecular Formula	C₁₆H₉F₃N₂O
Molecular Weight	302.25 g/mol
Synonyms	4-Pyrazolecarboxaldehyde, 1-(2,4-difluorophenyl)-3-(4-fluorophenyl)-1H-; 1-(2,4-Difluorophenyl)-3-(4-fluorophenyl)-1H-pyrazole-4-carboxaldehyde; 1H-Pyrazole-4-carboxaldehyde, 1-(2,4-difluorophenyl)-3-(4-fluorophenyl)-; 4-Formyl-1-(2,4-difluorophenyl)-3-(4-fluorophenyl)pyrazole; Difluorophenyl Fluorophenyl Pyrazole Carbaldehyde; Pyrazole Carbaldehyde Derivative CAS 618098-78-5
EINECS	Contact for details

Quality Control

Our 1-(2,4-Difluorophenyl)-3-(4-Fluorophenyl)-1H-Pyrazole-4-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and regulated production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive. Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.