Description

4,6-Dichloro-2-Cyclopropyl-5-Fluoropyrimidine is a high-purity fluorinated pyrimidine derivative, a crucial advanced pharmaceutical intermediate (API) in modern synthetic chemistry. Its core value lies in its unique halogenated structure, which serves as a versatile building block for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for antiviral and anticancer drug candidates.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging the biological activity of the fluoropyrimidine core.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and the discovery of new chemical entities.
• Custom Synthesis Building Block: Employed in contract manufacturing and custom synthesis for producing specialized, high-value fine chemicals.
• Material Science Applications: Potential use in the synthesis of specialty polymers or organic electronic materials due to its halogenated aromatic system.

Basic Information

Item	Detail
Product Name	4,6-Dichloro-2-Cyclopropyl-5-Fluoropyrimidine
CAS No.	617716-22-0
Molecular Formula	C7H5Cl2FN2
Molecular Weight	207.03 g/mol
Synonyms	2-Cyclopropyl-4,6-dichloro-5-fluoropyrimidine; 5-Fluoro-4,6-dichloro-2-cyclopropylpyrimidine; 4,6-Dichloro-5-fluoro-2-cyclopropylpyrimidine; 617716-22-0; Fluorinated Pyrimidine Intermediate; Dichlorofluorocyclopropylpyrimidine
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-2-Cyclopropyl-5-Fluoropyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.