Description

Gatifloxacin Hydrate CAS NO 614751-80-3 is a synthetic broad-spectrum fluoroquinolone antibiotic. It is a critical active pharmaceutical ingredient (API) valued for its potent activity against a wide range of Gram-positive and Gram-negative bacteria. This compound is essential for pharmaceutical manufacturers developing ophthalmic solutions, oral medications, and other antimicrobial formulations.

Application

• Pharmaceutical API: Primary use as the active ingredient in the synthesis of antibiotic medications.
• Ophthalmic Solutions: Formulation of eye drops and ointments for treating bacterial conjunctivitis and corneal ulcers.
• Oral Solid Dosage Forms: Manufacture of tablets and capsules for systemic antibacterial therapy.
• Veterinary Medicine: Development of antibacterial treatments for companion and livestock animals.
• Research & Development: Used as a reference standard and in preclinical studies for novel antimicrobial agents.
• Intermediate Synthesis: Serves as a key intermediate for further chemical modification in drug discovery.

Basic Information

Product Name	Gatifloxacin Hydrate
CAS No.	614751-80-3
Molecular Formula	C19H22FN3O4 • xH2O
Molecular Weight	375.40 g/mol (anhydrous basis)
Synonyms	Gatifloxacin Monohydrate; (±)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid hydrate; AM-1155; BMS-206584; Gatiflo; Tequin (Brand Name); Zymar (Brand Name); Gatiquin
EINECS	Contact for details

Quality Control

Our Gatifloxacin Hydrate is manufactured under strict quality management systems. It is produced to meet high-purity standards suitable for pharmaceutical applications, with typical specifications aligning with major pharmacopoeial guidelines. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with each batch to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The container should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC, anhydrous basis)	98.0% - 102.0%
Water Content (KF)	3.0% - 6.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Complies with Ph. Eur. 2.6.12 / USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.