Description

4-[(3-Fluorophenoxy)Methyl]Piperidinehydrochloride is a high-purity, fluorinated piperidine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a fluorophenoxy moiety, makes it a valuable intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorinated aromatic group enhances bioactivity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or structural properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	4-[(3-Fluorophenoxy)Methyl]Piperidinehydrochloride
CAS No.	614731-38-3
Molecular Formula	C12H16FNO•HCl
Molecular Weight	245.72 g/mol (Free base: 209.26 g/mol)
Synonyms	4-[(3-Fluorophenoxy)methyl]piperidine hydrochloride; 1-[(3-Fluorophenoxy)methyl]piperidin-4-ium chloride; Piperidine, 4-[(3-fluorophenoxy)methyl]-, hydrochloride; 4-(3-Fluorophenoxymethyl)piperidine HCl; 3-Fluoro-4-piperidinomethoxyphenyl hydrochloride
EINECS	Contact for details

Quality Control

Our 4-[(3-Fluorophenoxy)Methyl]Piperidinehydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.