Description

1-(Chloromethyl)-4-[(4-Fluorophenyl)Methoxy]Benzene CAS NO 613240-41-8 is a specialized aromatic ether derivative featuring both chloromethyl and fluorophenyl functional groups, making it a versatile and valuable synthetic intermediate. This compound is engineered for high reactivity, enabling precise chemical transformations in complex organic synthesis. It is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for constructing advanced molecular scaffolds in active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging its fluorinated aromatic structure.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated aromatic cores used in electronic display technologies.
• Polymer Modification Agent: Employed to introduce functional groups into polymer chains to alter physical properties like solubility and thermal stability.
• Cross-coupling Reactions: Acts as a substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions for carbon-carbon bond formation.
• Organic Ligand Synthesis: Utilized in the preparation of complex ligands for catalysis and material science applications.

Basic Information

Product Name	1-(Chloromethyl)-4-[(4-Fluorophenyl)Methoxy]Benzene
CAS No.	613240-41-8
Molecular Formula	C14H12ClFO
Molecular Weight	250.70 g/mol
Synonyms	4-[(4-Fluorobenzyl)oxy]benzyl chloride; 1-(Chloromethyl)-4-[(4-fluorophenyl)methoxy]benzene; (4-((4-Fluorobenzyl)oxy)phenyl)methanol chloride; p-[(p-Fluorobenzyl)oxy]benzyl chloride; 4-Fluorobenzyl 4-(chloromethyl)phenyl ether; Benzene, 1-(chloromethyl)-4-[(4-fluorophenyl)methoxy]-; [4-[(4-Fluorophenyl)methoxy]phenyl]methyl chloride
EINECS	Contact for details

Quality Control

Our 1-(Chloromethyl)-4-[(4-Fluorophenyl)Methoxy]Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for sensitive pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the light-sensitive nature of the compound, the container should be opaque or stored in darkness. Keep the container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.